Prostate Cancer Active Surveillance Failure

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Active surveillance failure for prostate cancer: does the

(1 days ago) Introduction: Active surveillance for low risk prostate cancer has become an acceptable management strategy. However, a percentage of these patients in active surveillance move on to active treatment. Our aim was to examine urinary incontinence (UI) rates in men who move on to treatment from active surveillance and compare it to quoted rates in the literature.

https://pubmed.ncbi.nlm.nih.gov/22704315/

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Active surveillance for prostate cancer

(3 days ago) Active surveillance (AS) is an approach that uses a combination of PSA testing, digital rectal examinations (DRE), and prostate biopsies to monitor prostate cancer in men rather than immediately advising treatment for low-risk/favorable-intermediate risk, localized prostate cancers (5-7). Some AS programs also incorporate magnetic resonance

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261451/

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Active Surveillance for Prostate Cancer Johns Hopkins

(8 days ago) This involves monitoring prostate cancer in its localized stage until your doctor feels that further treatment is needed to halt the disease at a curable stage. According to the American Society of Clinical Oncology, patients with low-risk, low-grade disease (a Gleason score of 6) can consider active surveillance.

https://www.hopkinsmedicine.org/health/conditions-and-diseases/prostate-cancer/active-surveillance-for-prostate-cancer

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Active Surveillance in Prostate Cancer: The 2021 NCCN

(5 days ago) Active Surveillance Background Prostate cancer represents a public health dilemma: while prostate cancer is the second leading cause of death among men in the US 1 and third in Canada, 2 it is widely over-diagnosed and over-treated, leading to significant patient anxiety and morbidity. 3 Much of the over-diagnosis of prostate cancer relates to the use of serum …

https://www.urotoday.com/library-resources/localized-prostate-cancer/134293-active-surveillance-in-prostate-cancer-the-2021-nccn-controversy.html

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Long-term outcomes of active surveillance for prostate

(3 days ago) Only 3 series (Prostate Cancer Research International Active Surveillance, Johns Hopkins, and Toronto) comprise more than 900 patients and have reported follow-up at 10 or 15 years. 15, 17–20 Moreover, because these cohorts used different eligibility criteria and regimens for follow-up, the 15-year prostate cancer mortality risk varies

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480884/

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Active surveillance for low-risk prostate cancer: New data

(9 days ago) Citation: Active surveillance for low-risk prostate cancer: New data on risk factors for switching to active treatment (2021, September 10) retrieved 15 January 2022 from https://medicalxpress.com

https://medicalxpress.com/news/2021-09-surveillance-low-risk-prostate-cancer-factors.html

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Active Surveillance and Prostate Cancer Prostate Cancer

(8 days ago) But studies show that men with low-risk prostate cancer who have been on Active Surveillance for 10 to 15 years after diagnosis have remarkably low rates of their disease spreading or dying of prostate cancer. In fact, a Johns Hopkins study of men on Active Surveillance found that, 15 years later, less than 1% of men developed metastatic disease.

https://www.pcf.org/about-prostate-cancer/prostate-cancer-treatment/active-surveillance/

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Men with Low-Risk Prostate Cancer in Active Surveillance

(5 days ago) Of the 1,298 men, 47 died of nonprostate cancer causes, mostly cardiovascular disease; nine of the 47 had received treatment for their prostate cancer. Two men died from prostate cancer, one after 16 years in the active surveillance program.

https://www.hopkinsmedicine.org/news/media/releases/men_with_low_risk_prostate_cancer_in_active_surveillance_program_not_likely_to_succumb_to_the_disease_study_shows

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Active surveillance in men with Gleason 3 + 4 = 7 prostate

(1 days ago) Unfavorable disease was defined as prostate cancer with a Gleason score of ≥ 4 + 3 = 7 or pathological stage T3 and biochemical failure (i.e., a post-surgical PSA level > 0.2 ng/ml). Here is a summary of the study findings: 359 men were initially enrolled on active surveillance and followed for an average (mean) of 72.9 months

https://prostatecancerinfolink.net/2018/04/19/active-surveillance-in-men-with-gleason-3-4-7-prostate-cancer-at-diagnosis/

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Active Surveillance for Prostate Cancer

(4 days ago) Active Surveillance for Prostate Cancer Did you know? Prostate cancer is the most common cancer in men in the United States. It is also the second leading cause of cancer death in men. But many prostate cancers may grow very slowly, and may not need to be treated right away if …

https://urology.ucsf.edu/sites/urology.ucsf.edu/files/uploaded-files/attachments/active_surveillance_for_prostate_cancer.pdf

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Active surveillance for intermediate-risk prostate cancer.

(7 days ago) Active surveillance (AS) is an established approach in the management of low-risk, localized prostate cancer. While the use of AS to manage intermediate-risk (IR) disease has gradually increased over time, there remains uncertainty with regards to its safety, with only a minority of IR patients currently being managed with this approach.

https://www.urotoday.com/recent-abstracts/urologic-oncology/prostate-cancer/134895-active-surveillance-for-intermediate-risk-prostate-cancer-2.html

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Active Surveillance for Prostate Cancer: How to Do It Right

(6 days ago) Oncology (Williston Park). 31 (5):333-340, 345. Figure. Active Surveillance Is a Conservative Management Approach, Appropriate for Many Patients With Low-Risk Prostate Cancer, That Can Reduce the Adverse Effects on Quality of Life Associated With Immediate Active Treatment. Table 1.

https://www.cancernetwork.com/view/active-surveillance-prostate-cancer-how-do-it-right

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The Prostate Cancer Active Surveillance Project Dr. Catalona

(7 days ago) Catalona’s current SPORE project, entitled The Impact of genetic variants on failure of active surveillance for prostate cancer, is the largest genetic association study to date of men on active surveillance, with more than 6,400 men participating.* The goal of the SPORE project is to identify germline genetic variants that are associated

https://drcatalona.com/quest/the-prostate-cancer-active-surveillance-project/

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Prostate Cancer: Active Surveillance

(2 days ago) Prostate Cancer: Active Surveillance. Not every person with prostate cancer needs to be treated right away. In many cases, early-stage prostate cancer will not spread or cause any problems or side effects for a long time, if ever. That’s why your healthcare provider may suggest active surveillance.

https://myhealth.ucsd.edu/Search/34,AProT1

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Active Surveillance ZERO - The End of Prostate Cancer

(5 days ago) Active surveillance is a disease management strategy for low-risk early stage prostate cancer. This strategy monitors the disease for progression but avoids immediate treatment with surgery or radiation. Who should consider active surveillance? Men with low-risk, early stage prostate cancer can discuss active surveillance with their doctor. As

https://zerocancer.org/learn/current-patients/types-of-treatment/active-surveillance/

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Active Surveillance for prostate cancer – is it right for

(4 days ago) 21 August 2020. If you have low risk prostate cancer, Active Surveillance is increasingly being recommended as a management option for your disease, in order to avoid unnecessary and invasive treatments when it is clinically safe to do so. Estimates suggest about 60% of low risk prostate cancers in Australia are managed with Active Surveillance.

https://www.prostate.org.au/news-media/news/active-surveillance-for-prostate-cancer-is-it-right-for-you/

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Active surveillance for intermediate-risk prostate cancer

(8 days ago) Download Citation Active surveillance for intermediate-risk prostate cancer Introduction Active surveillance (AS) is an established approach in the …

https://www.researchgate.net/publication/357947254_Active_surveillance_for_intermediate-risk_prostate_cancer

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Active surveillance prostate cancer. — Cancer Survivors

(6 days ago) At Johns Hopkins for example, the criteria for them to accept a man in an active surveillance program, are two cores or less out of 12 with a 3+3=6 with less than 50 percent involvement in each of the cores that are positive. A PSA under 10 with normal or slight bump in prostate, Ratio PSA/Prostate size less than 0.15.

https://csn.cancer.org/discussion/321553/active-surveillance-prostate-cancer

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Active Surveillance For Prostate Cancer: What It Is

(9 days ago) What Does Active Surveillance Mean? A patient with localized prostate cancer can opt for active surveillance. But, cancer must be slow-raising, confined, and low-grade. Active surveillance is a monitoring routine where a physician will closely assess the disease until additional or definitive treatment becomes necessary to halt cancer at a curable stage.

https://www.bensnaturalhealth.com/blog/active-surveillance-for-prostate-cancer/

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Active Surveillance - Prostate Cancer

(5 days ago) Reuters Health Information Study Confirms Safety of Active Surveillance in Low-Risk Prostate Cancer By Reuters Staff July 07, 2016 NEW YORK (Reuters Health) – After a decade of follow-up in the Prostate Cancer Research International Active Surveillance (PRIAS) study, researchers have confirmed that active surveillance is a safe treatment option for men …

https://www.prostate-cancer.org.au/active-surveillance/

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Prostate Cancer Cohor Shows Where Active Surveillance Works

(1 days ago) Active surveillance for lower-risk prostate cancer patients produced a high rate of metastasis-free survival, with only a handful of …

https://www.ajmc.com/view/prostate-cancer-cohort-shows-where-active-surveillance-presents-lowest-risk

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A biopsy-integrated algorithm for determining Gleason 6

(1 days ago) Introduction: A significant proportion of patients that fail active surveillance (AS) for prostate cancer management do so because of cancer upgrading. A previously validated upgrading nomogram generates a score that predicts risk of biopsy Gleason 6 upgrading following radical prostatectomy in lower-risk populations that are candidates for Active Surveillance (Cancer, …

https://pubmed.ncbi.nlm.nih.gov/27631325/

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Prostate Cancer Active Surveillance - Prostate cancer

(9 days ago) Prostate Cancer Active Surveillance. stp1234. Jun 21, 2021, 9:41:03 AM. I am continuing my Active Surveillance since 2013 for Gleason 6 Prostate Cancer (Pc). I have had 4 biopsies since 2013 with 3 of the 4 biopsies finding one or two positive cores of Gleason 6 PC. My last Biopsy was at Hopkins in Nov 2019.

https://www.inspire.com/groups/zero-prostate-cancer/discussion/prostate-cancer-active-surveillance/

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Prostate Cancer Active Surveillance Cedars-Sinai

(4 days ago) For optimal success with active surveillance, patients are also encouraged to maintain a healthy lifestyle because men with prostate cancer are at higher risk of heart disease. Metabolic syndrome, which brings serious risks such as high blood pressure and Type 2 diabetes, is also more common among men with prostate cancer.

https://www.cedars-sinai.org/blog/prostate-cancer-active-surveillance.html

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Active Surveillance: Good News for Men with Low-Risk

(9 days ago) The Brady's Active Surveillance program has reached a milestone: 20 years of carefully following men with low-risk prostate cancer. "What we have learned since 1995 can help many men with low-grade, low-risk prostate cancer, and their doctors, determine their best course of treatment," says urologist H. Ballentine Carter, M.D., the Bernard L. Schwartz …

https://clinicalconnection.hopkinsmedicine.org/news/active-surveillance-good-news-for-men-with-low-risk-prostate-cancer

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Active Surveillance of Prostate Cancer

(Just Now) Active Surveillance of Prostate Cancer. January 15, 2017. Peter L. Choyke, MD , Stacy Loeb, MD, MSc. Active surveillance is an excellent alternative to surgery or radiation in patients with low-risk cancers. However, the current methods of ascertaining whether a patient harbors a low-risk cancer are flawed. Introduction.

https://www.cancernetwork.com/view/active-surveillance-prostate-cancer

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NCCN Reverses on Guideline Change for Surveillance in

(7 days ago) "Active surveillance really should be the default plan for a man with low-grade prostate cancer, regardless of tumor volume, and the 'preferred' designation more or less reflects that assumption."

https://www.medpagetoday.com/urology/prostatecancer/95949

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Risk calculators for men already on active surveillance

(2 days ago) The Prostate Active Surveillance Study (PASS), initially funded by the Canary Foundation, is a multi-center research study for men with low-risk disease who have chosen active surveillance (AS) to manage their prostate cancer.Active surveillance in PASS means closely monitoring men with prostate cancer and offering treatment if test results show the …

https://prostatecancerinfolink.net/2020/08/29/risk-calculators-for-men-already-on-active-surveillance/

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A Randomized Study of Enzalutamide in Patients With

(7 days ago) A Randomized Study of Enzalutamide in Patients With Localized Prostate Cancer Undergoing Active Surveillance (ENACT) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators.

https://clinicaltrials.gov/ct2/show/NCT02799745

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(PDF) Understanding reasons for non-adherence to active

(8 days ago) Background Active surveillance (AS) is recommended by most national medical organizations as the preferred treatment option for men with low-risk prostate cancer (PCa). However, studies report that up to one third of men on AS dropout within 5 years,

https://www.academia.edu/68487617/Understanding_reasons_for_non_adherence_to_active_surveillance_for_low_intermediate_risk_prostate_cancer

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Enhancing active surveillance of prostate cancer: the

(6 days ago) Active surveillance for low-risk prostate cancer worldwide: the PRIAS study. Eur. Urol. 63, 597–603 (2013). PubMed Google Scholar 7. Klotz, L. …

https://www.nature.com/articles/nrurol.2016.46

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Active surveillance for prostate cancer

(1 days ago) Active surveillance for prostate cancer is used to avoid treatment side effects when the risk of the prostate cancer progressing is very low. such as severe heart disease -- …

https://www.msn.com/en-us/health/medical/active-surveillance-for-prostate-cancer/ar-AAQm5Hj

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Active Surveillance for Prostate Cancer – Cleveland Clinic

(5 days ago) Active surveillance is often recommended for low-risk prostate cancer (or intermediate-risk disease). But for it to work, you have to actively adhere to …

https://health.clevelandclinic.org/doing-active-surveillance-for-prostate-cancer-heres-why-you-need-to-be-vigilant/

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EAU Guidelines: Prostate Cancer Uroweb

(9 days ago) Active surveillance is an option in patients with the lowest risk of cancer progression: > 10 years life expectancy, cT1/2, PSA ≤ 10 ng/mL, biopsy Gleason score ≤ 6, ≤ 2 positive biopsies, minimal biopsy core involvement (≤ 50% cancer per biopsy).

https://uroweb.org/guideline/prostate-cancer/?type=summary-of-changes

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Active surveillance for prostate cancer at Penn State

(7 days ago) Repeat prostate biopsies, with or without MRI fusion, are repeated every one to three years. “We want to catch any disease progression immediately,” says Dr. Kaag, who estimates about 30% of his prostate cancer patients …

https://medicalupdate.pennstatehealth.org/urology-surgery/prostate-cancer-surveillance/

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Active Surveillance for Prostate Cancer Cedars-Sinai

(4 days ago) Overview. One of the newest paradigms in prostate cancer care is to monitor eligible patients, those with low-grade prostate cancer, through an active surveillance program.. Active surveillance is the merging of watchful waiting and active management into a program that is interactive for the patient, ultimately allowing a man diagnosed with prostate cancer to …

https://www.cedars-sinai.org/health-library/diseases-and-conditions/a/active-surveillance-for-prostate-cancer.html

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Regional Variation in Active Surveillance for Low-Risk

(8 days ago) Prostate cancer remains the second most common cause of cancer deaths in US men; however, the incidence exceeds mortality rates, and men with low-risk disease are at risk of possible overtreatment. 1 Active surveillance (AS) can reduce the risk of morbidity associated with definitive treatments, such as radical prostatectomy or radiotherapy, 2

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2774494

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How to Do Active Surveillance for More Heart Health, Less

(8 days ago) As designed, the trial was named The Exercise During Active Surveillance for Prostate Cancer (ERASE). Between 2018-2020, a total of 52 otherwise healthy PCa patients were enrolled in the study. One half (26 men) were randomly assigned to receive usual care while the other half was assigned to a high intensity interval training group (HIIT).

https://sperlingprostatecenter.com/how-to-do-active-surveillance-for-more-heart-health-less-prostate-cancer/

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Sarah Birken, PhD, and Soohyun Hwang on Active

(8 days ago) National guidelines on active surveillance for patients with low-risk prostate cancer are commonly not followed by urologists, and …

https://www.medpagetoday.com/reading-room/asco/prostate-cancer/96528

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We've Never Really Understood the Prostate MedPage Today

(7 days ago) 2 days ago · In my view, Johnson should have written a chapter on active surveillance, a strategy that could help the majority of the 1.4 million men globally who annually are diagnosed with prostate cancer

https://www.medpagetoday.com/special-reports/apatientsjourney/96753

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Prostate Cancer: Clinically Localized Guideline - American

(1 days ago) Published 2017. These guidelines for the management of localized prostate cancer are structured first, to provide a clinical framework stratified by cancer severity to facilitate care decisions and second, to guide the specifics of implementing the selected management options, including active surveillance, observation/watchful waiting, prostatectomy, …

https://www.auanet.org/guidelines/guidelines/prostate-cancer-clinically-localized-guideline

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Guidelines for the Management of Prostate Cancer

(4 days ago) 12.5.1 Active surveillance is best suited to men with low-risk disease 12.5.2 Active surveillance protocol PSA estimation (including doubling time (DT)) and DRE every 3-6 months. Early MRI and rebiopsy after 12 months (TRUSS-guided or template). 12.5.3 Active surveillance - progression to treatment: PSA DT of 2 years or less Evidence of disease

https://www.england.nhs.uk/mids-east/wp-content/uploads/sites/7/2018/05/guidelines-for-the-management-of-prostate-cancer.pdf

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Active Surveillance in Prostate Cancer — Metrovan Urology

(7 days ago) About 3% of men on active surveillance protocols are expected to die from prostate cancer 20 years after diagnosis (and virtually no one within the first 5-10 years) compared with 1.6% of men who undergo immediate surgery. 3.4% of men on surveillance vs. 2.0% of men undergoing immediate surgery would die of prostate cancer during their lifetime.

https://www.metrovanurology.com/prostate-cancer-active-surveillance

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Prostate Cancer Active Surveillance in 2019 Sigrid V

(9 days ago) Only a small proportion of men with prostate cancer die from the disease. Treatment with radical prostatectomy leads to worse long-term morbidity compared to active surveillance. Many trials, such as the PIVOT trial, have confirmed the safety of active surveillance in patients with low-risk prostate cancer. Even so, many patients with low-risk

https://grandroundsinurology.com/prostate-cancer-active-surveillance-in-2019-2/

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